Cloned glutamic acid decarboxylase
US6682906B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 21, 1990 |
| Grant date | Jan 27, 2004 |
| Priority date | — |
| Expiry date | Sep 21, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/042
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
cDNA molecules coding for GAD65 polypeptide are disclosed. The invention provides cDNA molecules comprising a part of the cDNA sequence of GAD65 which encode at least one epitope for autoantibodies to GAD65. The invention also provides cloning vehicles capable of replication and expression comprising cDNA molecules coding for GAD65. The invention further provides for hosts transformed with a vehicle having a cDNA molecule coding for GAD65. In another embodiment, the invention provides for the detection of autoantibodies to GAD65 using the GAD65 polypeptides coded for by the cDNA molecules of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.