Patent · US Expired

Formulations for treating or preventing mucositis

US6683067B2 · kind B2 · utility

3Cited by
15References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 23, 2001
Grant dateJan 27, 2004
Priority date—
Expiry dateNov 3, 2021

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K47/36
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Mucositis is treated and/or prevented by administrating to a patient a formulation comprising a tetracycline that is poorly absorbed from the gastro-intestinal tract. The tetracycline may be in the form of a pharmaceutically acceptable salt or a base. The formulations may optionally also contain an antifungal agent to prevent fungal overgrowth due to reduction in the normal oral flora by the tetracycline. Such compositions have the advantage of treating the entire gastro-intestinal tract since the active ingredient is not removed from the tract via absorption. Further, such compositions minimize systemic exposure and accompanying side effects.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.