Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
US6683155B1 · kind B1 · utility
9Cited by
3References
17Claims
0Family size
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Key dates
| Filing date | Oct 9, 1996 |
| Grant date | Jan 27, 2004 |
| Priority date | — |
| Expiry date | Jul 23, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/8146
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention reveals a class of novel inhibitors of metalloproteinase. For convenience, these polypeptides are referred to as “TIMP-3”, as these polypeptides represent a new class of members of the tissue inhibitors of metalloproteinases. Also provided are DNA sequences coding for all or part of the TIMP-3s, vectors containing such DNA sequences, and host cells transformed or transfected with such vectors. In addition, methods of producing recombinant TIMP-3s, methods of treating disorders, pharmaceutical compositions including TIMP-3s and antibodies selectively binding TIMP-3s are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.