Enantiomeric compounds for treatment of cardiac arrhythmias and methods of use
US6683195B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 2002 |
| Grant date | Jan 27, 2004 |
| Priority date | — |
| Expiry date | Apr 15, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/80
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The subject invention pertains to novel enantiomerically pure compounds, and compositions comprising the compounds, for the treatment of cardiac arrhythmias. The subject invention further concerns a method of making and purifying the compounds. The enantiomerically purified compounds, and compositions of these compounds, exhibit unexpectedly distinct and advantageous characteristics, such as a markedly superior ability to reduce or inhibit ventricular premature beats, as compared to racemic mixtures of the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.