Magnetic resonance force microscope for the study of biological systems
US6683451B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 2, 2000 |
| Grant date | Jan 27, 2004 |
| Priority date | — |
| Expiry date | Oct 2, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/96
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A high resolution magnetic resonance force microscope is adapted to study biological systems, such as isolated cells, sub-cellular organelles and other sub-cellular structures, or cellular receptors and proteins, at resolutions ranging from 1 micron to 1 å. The proposed magnetic resonance force microscope allows the direct, non-destructive, chemical specific, three-dimensional imaging of biological systems. In some embodiments, the biological sample may be altered to enhance its ability to be detected by its nuclear or electron spin resonance. In a particularly preferred embodiment, a paramagnetic agent is incorporated into cells by endocytosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.