Methods for identifying agents that interact with an active site of acyl carrier protein synthase-acyl carrier protein complex
US6684162B2 · kind B2 · utility
1Cited by
1References
36Claims
0Family size
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Key dates
| Filing date | Jan 25, 2001 |
| Grant date | Jan 27, 2004 |
| Priority date | — |
| Expiry date | Jan 25, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B15/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
This invention is directed to the crystal structure of Acyl Carrier Protein Synthase (ACPS) complexed with Acyl Carrier Protein (ACP), the solution structure of B. subtilis ACP, and to the use of these structures in rational drug design methods to identify agents that may interact with active sites of ACPS and ACP, and to the testing of these agents to identify agents that may represent novel antibiotics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.