Inhibitors of &agr;4&bgr;1 mediated cell adhesion
US6685617B1 · kind B1 · utility
9Cited by
11References
9Claims
0Family size
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Inventors
Key dates
| Filing date | Mar 9, 2001 |
| Grant date | Feb 3, 2004 |
| Priority date | — |
| Expiry date | Mar 9, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06139
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compound of formula (I), that are potent inhibitors of &agr;4&bgr;1 mediated adhesion to either VCAM or CS-1 and which could be useful for the treatment of inflammatory diseases. Specifically, the molecules of the present invention can be used for treating or preventing &agr;4&bgr;1 adhesion mediated conditions in a mammal such as a human. This method may comprise administering to a mammal or a human patient an effective amount of the compound or composition as explained in the present specification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.