Sensitization process for antigen-presenting cells and means for implementing the process
US6685911B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 15, 1999 |
| Grant date | Feb 3, 2004 |
| Priority date | — |
| Expiry date | Mar 15, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2239/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The object of the invention is a novel sensitization process for antigen-presenting cells, novel means for implementing the process and novel membrane vesicles possessing immunogenic potency. The invention relates in particular to texosomes (vesicles derived from tumor cells) and dexosomes (vesicles derived from dendritic cells loaded or not with antigens), and their use for the vectorization and presentation of antigens in vitro or in vivo as well as in methods or compositions for the treatment of cancers and infectious, parasitic or autoimmune diseases in particular.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.