Post-labeling stabilization of radiolabeled proteins and peptides
US6685912B2 · kind B2 · utility
5Cited by
20References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 30, 2002 |
| Grant date | Feb 3, 2004 |
| Priority date | — |
| Expiry date | Apr 30, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K51/121
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention relates to the use of ascorbic acid and derivatives thereof in stabilizing radiolabeled proteins and peptides against oxidation loss of radiolabel and autoradiolysis. Ascorbic acid is added after radiolabeling, including any required incubation period, but prior to patient administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.