Pharmaceutical compositions comprising 2-isoxazoles-8-aminotetralin derivatives

US6685959B1 · kind B1 · utility

Assignee

• Société de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS · FR

Inventors

• Jacques-Pierre Moreau · Upton, US
• Béatrice Guimbert · Huest, FR
• Marc Pellet · L'Aigle, FR

Key dates

• Filing date: Jan 30, 2002
• Grant date: Feb 3, 2004
• Expiry date: Jan 30, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P1/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel pharmaceutical compositions comprising 2-isoxazole-8-aminotetralin derivatives. The invention more specifically relates to compositions in the form of a patch comprising a therapeutically efficacious amount of a derivative of 2-isoxazole-8-aminotetraline, especially 1,2,3,4-tetrahydro-8(5-isoxazolyl)N-N-diisopropyl-2-naphtalenamine. The invention also relates to a 2-isoxazole-8-aminotetralin derivative, especially 1,2,3,4-tetrahydro-8-(5-isoxazolyl)-N,N-diisopropyl-2-naphtalenamine, which is used to produce a medicament which can be administered transdermally to treat irritable bowel syndrome.