Process for isolating artemisinin from Artemisia annua

US6685972B2 · kind B2 · utility

Assignee

• COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH · IN

Inventors

• Sushil Kumar · Lucknow, IN
• Shiv Kumar Gupta · Lucknow, IN
• Digvijay Singh · Lucknow, IN
• Madan Mohan Gupta · Sidhauli, IN
• Dharam Chand Jain · Lucknow, IN
• Atul Prakash Kahol · Lucknow, IN
• Suman Preet Singh Khanuja · Lucknow, IN
• Govind Ram · Sidhauli, IN

Key dates

• Filing date: Mar 27, 2002
• Grant date: Feb 3, 2004
• Expiry date: Mar 27, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K36/282
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for the isolation of artemisinin, an antimalarial agent from the herb of the Artemisia annua plant, comprising of extracting the herb with ethanol, partitioning of the extract between water and hexane, followed by evaporative crystallization of artemisinin from hexane phase to produce substantially pure artemisinin.