Fusion polypeptides of human serum albumin and a therapeutically active polypeptide

US6686179B2 · kind B2 · utility

Assignee

• Aventis Behring L.L.C. · US

Inventors

• Reinhard Fleer · Les Ulis, FR
• Alain Fournier · ᐙᔂᓂᐲ Waswanipi, CA
• Jean-Dominique Guitton · Paris, FR
• Gerard Jung · Montlhéry, FR
• Patrice Yeh · Paris, FR

Key dates

• Filing date: Oct 29, 2001
• Grant date: Feb 3, 2004
• Expiry date: Oct 29, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/33
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.