Metalloprotease inhibitors

US6686348B2 · kind B2 · utility

Assignee

• LES LABORATOIRES SERVIER · FR

Inventors

• Guillaume De Nanteuil · Suresnes, FR
• Alain Benoist · Franconville, FR
• Philippe Pastoureau · Sèvres, FR
• Massimo Sabatini · Garches, FR
• John Hickman · Paris, FR
• Alain Pierre · Marly-le-Roi, FR
• Gordon Tucker · Paris, FR

Key dates

• Filing date: Dec 21, 2001
• Grant date: Feb 3, 2004
• Expiry date: Apr 23, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A compound of formula (I): wherein:R1 represents hydrogen, halogen, alkyl or alkoxy,X represents oxygen, sulphur or NR wherein R represents hydrogen or alkyl,A represents any one of the groups described in the description,their isomers and addition salts thereof with a pharmaceutically acceptable acid or base and medicinal products containing the same are useful as metalloprotease inhibitor.