Patent · US Expired

Bicyclic amino-pyrazinone compounds

US6686358B2 · kind B2 · utility

10Cited by
1References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 14, 2001
Grant dateFeb 3, 2004
Priority date
Expiry dateDec 28, 2021

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A compound of formula (I): wherein:R1 represents hydrogen, or linear or branched (C1-C6)alkyl optionally substituted by one or more identical or different groups selected from aryl, heteroaryl, cycloalkyl and heterocycloalkyl, represents a saturated ring having from 4 to 7 ring members that may contain, in addition to nitrogen, one or two hetero atoms selected from O, S and —NR3 groups, wherein R3 represents hydrogen or linear or branched (C1-C6)alkyl,n represents an integer such that 1≦n≦6,R2 represents any one of the groups described in the description,their isomers and addition salts thereof with a pharmaceutically acceptable acid or base and medicinal products containing the same are useful as inhibitor of trypsin-related serine proteases and thrombin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.