Skin protection agents containing a fragment mixture produced from hyaluronic acid by hydrolysis

US6689349B1 · kind B1 · utility

Assignee

• Esparma GmbH · DE

Inventors

• Wolfgang Wohlrab · Bodenwerder, DE
• Reinhard Neubert · Bodenwerder, DE
• Christoph Huschka · Bodenwerder, DE
• Peter-Jürgen Müller · Jena, DE
• Jörg-Herman Ozegowski · Jena, DE
• Dieter Koegst · Osterweddingen, DE
• Gerhard Fries · Gommern, DE

Key dates

• Filing date: Sep 10, 2001
• Grant date: Feb 10, 2004
• Expiry date: Sep 10, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61Q17/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to an agent for the treatment, prophylaxis and metaphylaxis of functional and structural disorders of the skin caused by external factors. The agent contains a hyaluronic acid partially digested with a microbiological hyaluronate lyase. The hyaluronic acid fragment mixture is incorporated in different galenic formulations to which other hydrophilic and/or lipophilic active substances and/or auxiliary substances can be added. Fields of application of the invention in human and veterinary medicine relate to the treatment and/or the prophylaxis of skin damage caused by environmental factors including UV, dry skin conditions and skin ageing.