Liposomal benzoquinazoline thymidylate synthase inhibitor formulations
US6689381B2 · kind B2 · utility
1Cited by
4References
67Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 6, 2001 |
| Grant date | Feb 10, 2004 |
| Priority date | — |
| Expiry date | Jun 6, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Liposomal encapsulated benzoquinazoline thymidylate synthase inhibitor formulations are provided. The liposomes have improved pharmacokinetics and enhanced efficacy as anti-tumor agents compared to the free drug. The formulations include liposomes comprising at least one phosphatidylcholine, a cholesterol, and a benzoquinazoline thymidylate synthase inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.