&bgr; sheet breaker peptide analogs that inhibit &bgr; pleated sheet formation in amyloid &bgr;-peptide
US6689753B1 · kind B1 · utility
22Cited by
6References
27Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 4, 2000 |
| Grant date | Feb 10, 2004 |
| Priority date | — |
| Expiry date | May 7, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides peptide analogs and peptide mimetics that inhibit pleated sheet formation in amyloid &bgr;-peptide, pharmaceutical compositions thereof and their therapeutic use. The inhibitory peptides possess activity as inhibitors in the formation of amyloid-like deposits and are useful in the treatment of Alzheimer's Disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.