Spectral bio-imaging data for cell classification using internal reference
US6690817B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 18, 1998 |
| Grant date | Feb 10, 2004 |
| Priority date | — |
| Expiry date | Sep 18, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6417
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of spectral-morphometric analysis of biological samples, the biological samples including substantially constant components and suspected variable components, the method is effected by following the steps of (a) using a spectral data collection device for collecting spectral data of picture elements of the biological samples; (b) defining a spectral vector associated with picture elements representing a constant component of at least one of the biological samples; (c) using the spectral vector for defining a correcting function being selected such that when operated on spectral vectors associated with picture elements representing other constant components, spectral vectors of the other constant components are modified to substantially resemble the spectral vector; (d) operating the correcting function on spectral vectors associated with at least the variable components for obtaining corrected spectral vectors thereof; and (e) classifying the corrected spectral vectors into classification groups.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.