Method for identifying agents which modulate chemokine “MEC”-induced functions of CCR3
US6692922B2 · kind B2 · utility
0Cited by
1References
26Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 15, 2001 |
| Grant date | Feb 17, 2004 |
| Priority date | — |
| Expiry date | Nov 1, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the interaction of MEC with CCR3 and/or CCR10 and to agents (e.g., ligands, antibodies, antagonists, agonists, inhibitors, promoters) which alter said interaction. In one aspect, the invention relates to methods for detecting or identifying an agent (i.e., molecule or compound) which can modulate (inhibit, promote) the binding of MEC to CCR3 and/or CCR10. In another aspect, the invention relates to a method of treating a subject having an inflammatory condition, comprising administering to the subject an effective amount of an agent which modulates the binding of MEC to CCR3 and/or CCR10.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.