Patent · US Expired

Targeted hetero-association of recombinant proteins to multi-functional complexes

US6692935B1 · kind B1 · utility

5Cited by

0References

26Claims

0Family size

Assignee

MORPHOSYS AG · DE

Inventors

Peter Pack · Unterföhring, DE
Andrei Lupas · Unterhaching, DE

Key dates

Filing date	May 30, 2000
Grant date	Feb 17, 2004
Priority date	—
Expiry date	Jun 20, 2020

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a method for targeted assembly of distinct active peptide or protein domains into a single complex and to such complexes. The invention relates particularly to the fusion of peptide or protein domains to complementary association domains which are derived from a single tertiary or quaternary structure by segmentation. The association domains are designed to assemble in a complementary fashion, thereby providing multifunctional (poly)peptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.