Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation

US6693109B2 · kind B2 · utility

Assignees

• ELI LILLY AND COMPANY · US
• Millennium Pharmaceuticals, Inc. · US

Inventors

• Matthew Joseph Fisher · Mooresville, US
• Joseph A. Jakubowski · Indianapolis, US
• John Joseph Masters · Fishers, US
• Jeffrey Thomas Mullaney · Indianapolis, US
• Michael Paal · Hamburg, DE
• Gerd Ruhter · Hamburg, DE
• Kenneth J. Ruterbories · Indianapolis, US
• Robert M. Scarborough · Belmont, US
• Theo Schotten · Winsen (Luhe), DE
• Wolfgang Stenzel · Reinbek, DE

Key dates

• Filing date: Jan 29, 2003
• Grant date: Feb 17, 2004
• Expiry date: Jan 29, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to certain spirocyclic compounds substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.