Spray drying of thrombin inhibitors

US6693120B1 · kind B1 · utility

Assignee

• Abbott GmbH & Co. KG · DE

Inventors

• Bernd Schaefer · Dierbach, DE
• Guido Harms · Schifferstadt, DE
• Hermann Ascherl · Dirmstein, DE
• Georg Arnold Krei · Altrip, DE

Key dates

• Filing date: Jul 2, 2002
• Grant date: Feb 17, 2004
• Expiry date: Jul 2, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a process for preparing constant-weight thrombin inhibitors of the formula I where n is 0, 1, 2, and tautomers thereof,wherein an aqueous solution of the active substance is spray dried.