Electro-powder
US6696090B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 11, 2000 |
| Grant date | Feb 24, 2004 |
| Priority date | — |
| Expiry date | Feb 9, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2202/064
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and a process are disclosed for preparation of medical electro-powders. The electro-powder results from preparations of chemical and biological substances to form electro-powders suitable for electrostatic charging and dosing for functionality in a dry powder inhaler device. The electro-powder resulting from the method and process forms an active powder substance or a dry powder medical formulation with a fine particle fraction representing of the order 50% or more of the content having a size ranging between 0.5-5 &mgr;m and provides electrostatic properties with an absolute specific charge per mass after charging of the order 0.1×10−6 to 25×10−6 C/g and presenting a charge decay rate constant Q50>0.1 sec with a tap density of less than 0.8 g/ml and a water activity aw of less than 0.5. In the processing the active substance is a generally pharmaceutical active chemical or biological substance, for instance a polyeptide or any other corresponding substance selected alone or mixed or blended together with one or more excipients being a compound to improve electrostatic properties of the medical dry powder substance or dry powder medical formulation.…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.