Methods to identify growth differentiation factor (GDF) binding proteins
US6696260B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 5, 2000 |
| Grant date | Feb 24, 2004 |
| Priority date | — |
| Expiry date | May 5, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides receptors for the growth differentiation factor (GDF) family of growth factors and methods of identifying such receptors. Also included are methods of identifying antibodies which bind to the receptors, peptide fragments of the receptor which inhibit GDF binding, GDF receptor-binding agents capable of blocking GDF binding to the receptor. The receptors of the invention allow the identification of antagonists or agonists useful for agricultural and human therapeutic purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.