Production and use of antimicrobial agents
US6696268B1 · kind B1 · utility
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3Claims
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Key dates
| Filing date | Mar 16, 2001 |
| Grant date | Feb 24, 2004 |
| Priority date | — |
| Expiry date | Mar 16, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/18
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for identifying antimicrobial agents comprises the steps of: (i) contacting a sample containing non-mammalian PPAT enzyme with a suitable substrate and a potential antimicrobial or antiprarasitic agent, under suitable conditions; (ii) measuring the activity of the PPAT enzyme; (iii) comparing the activity of the enzyme to that of a reference sample lacking the agent; and (iv) selecting an agent that reduces the activity of the PPAT enzyme.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.