Use of growth hormone in low dose

US6696414B2 · kind B2 · utility

Assignee

• Pharmacia AB · SE

Inventor

• David Dunger · Cambridge, GB

Key dates

• Filing date: Mar 13, 2001
• Grant date: Feb 24, 2004
• Expiry date: May 17, 2021

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S930/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to treatment of patients in need of increasing insulin sensitivity by administration of growth hormone or analogues thereof, preferably human growth hormone, in a low dose and the use of growth hormone or analogues thereof, preferably human growth hormone, for the manufacturing of a medicament useful for increasing insulin sensitivity in low dose therapy.The patient is preferably a normal subject, i.e. not growth hormone deficient patient and/or a non-obese patients.By low dose therapy is preferably meant less than 0.008 mg/kg/day, preferably 0.007 mg/kg/day or less, more preferably 0.005 mg/kg/day or less and most preferably 0.003 mg/kg/day or less.The therapy is preferably performed during short term treatment, preferably less than one month.