Covalent attachment of polymer to cell to prevent virus bonding to receptor
US6699465B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | May 18, 2001 |
| Grant date | Mar 2, 2004 |
| Priority date | — |
| Expiry date | Nov 13, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/22022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A chemo-physiological structure and method for forming the chemo-physiological structure. In a first embodiment, a cell of an animal is provided. The cell has a membrane surface and a viral receptor coupled to the membrane surface. A linker molecule having a covalently attached polymer is covalently bonded to the membrane surface, the viral receptor, or both. The polymer prevents an extracellular virus from bonding to the viral receptor. In a second embodiment, a linker molecule having a covalently attached polymer is covalently bonded to a capsid of a virus, which prevents the virus from bonding to a viral receptor of an adjacent or nearby animal cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.