Antimicrobial agents diagnostic reagents, and vaccines based on unique apicomplexan parasite components
US6699654B1 · kind B1 · utility
5Cited by
0References
9Claims
0Family size
Inventors
Key dates
| Filing date | Jun 23, 1998 |
| Grant date | Mar 2, 2004 |
| Priority date | — |
| Expiry date | Jun 23, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates uses of components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on the components and their inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.