Tethered ligands and methods of use
US6699677B1 · kind B1 · utility
11Cited by
2References
37Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 24, 2000 |
| Grant date | Mar 2, 2004 |
| Priority date | — |
| Expiry date | Aug 18, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides methods, reagents and devices for analysis of receptor ligand interactions, determining the profile of receptor expression in cells and cell populations, and diagnostic and drug screening methods. The invention makes use of immobilized tethered ligand fusion proteins having a ligand domain, a stalk domain, and optionally an immobilization domain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.