Patent · US Expired

Controlled- or delayed-release forms of topiramate

US6699840B2 · kind B2 · utility

28Cited by
19References
1Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 18, 2002
Grant dateMar 2, 2004
Priority date
Expiry dateNov 18, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H5/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as pharmaceutical compositions and pharmaceutical unit dosage forms containing the same. In particular, the invention encompasses pharmaceutically acceptable salts of topiramate, including without limitation topiramate sodium, topiramate lithium, topiramate potassium, or polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, and amorphous forms thereof. The invention further encompasses novel co-crystals or complexes of topiramate, as well as pharmaceutical compositions comprising them. The invention also encompasses methods of treating or preventing a variety of diseases and conditions including, but not limited to, seizures, epileptic conditions, tremors, cerebral function disorders, obesity, neuropathic pain, affective disorders, tobacco cessation, migraines, and cluster headache.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.