Substituted 1,2,3,4-tetrahydroquinoline-2-carboxylic acid derivatives

US6699877B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Matthias Gerlach · Wächtersbach, DE
• Michael Przewosny · Aachen, DE
• Werner Englberger · Stolberg, DE
• Elke Reissmueller · Bielefeld, DE
• Petra Bloms-Funke · Harsewinkel, DE
• Corinna Maul · Aachen, DE
• Utz-Peter Jagusch · Aachen, DE

Key dates

• Filing date: Aug 7, 2002
• Grant date: Mar 2, 2004
• Expiry date: Aug 7, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A substituted 1,2,3,4-tetrahydroquinoline-2-carboxylic acid derivative of formula I and salts thereof with pharmaceutically acceptable acids. Also disclosed are methods for making the derivative, and pharmaceutical compositions comprising the derivative. Methods for treating pain, migraine, and various other diseases using the pharmaceutical composition are also disclosed.