Reversible gelling system for ocular drug delivery
US6703039B2 · kind B2 · utility
40Cited by
20References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 6, 2000 |
| Grant date | Mar 9, 2004 |
| Priority date | — |
| Expiry date | Dec 6, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides an ophthalmic aqueous composition for topical administration, comprising:(a) a block copolymer of propylene oxide and ethylene oxide in concentration sufficient to provide viscosity of less than about 25 centipoise at ambient temperature and viscosity of from about 25 to about 55 centipoise when applied topically to a patient;(b) hydroxypropyl methylcellulose in concentration sufficient to improve the durability of the gel formed by the block copolymer.The invention further provides a method for administering ophthalmic pharmaceuticals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.