Methods and products related to genotyping and DNA analysis
US6703228B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 24, 1999 |
| Grant date | Mar 9, 2004 |
| Priority date | — |
| Expiry date | Sep 24, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B30/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention encompasses methods and products related to genotyping. The method of genotyping of the invention is based on the use of single nucleotide polymorphisms (SNPs) to perform high throughput genome scans. The high throughput method can be performed by hybridizing SNP allele-specific oligonucleotides and a reduced complexity genome (RCG). The invention also relates to methods of preparing the SNP specific oligonucleotides and RCGs, methods of fingerprinting, determining allele frequency for a SNP, characterizing tumors, generating a genomic classification code for a genome, identifying previously unknown SNPs, and related compositions and kits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.