Method of promoting bone growth with hyaluronic acid and growth factors
US6703377B2 · kind B2 · utility
1Cited by
39References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 3, 2001 |
| Grant date | Mar 9, 2004 |
| Priority date | — |
| Expiry date | Apr 3, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A bone growth-promoting composition is provided comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at an intra-articular site of desired bone growth for a period of time sufficient to promote the bone growth. Preferably hyaluronic acid is used in a composition range of 0.1-4% by weight and preferred growth factor is bFGF, present in a concentration range of about 10−6 to 100 mg/ml.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.