Patent · US Expired

1,2,3,4-tetrahydroisoquinoline derivatives

US6703392B2 · kind B2 · utility

9Cited by

1References

22Claims

0Family size

Assignee

Actelion Pharmaceuticals Ltd. · CH

Inventors

Hamed Aissaoui · Allschwil, CH
Michael W. Cappi · Hersbruck, DE
Martine Clozel · Binningen, CH
Walter Fischli · Allschwil, CH
Ralf Koberstein · Bad Kötzting, DE

Key dates

Filing date	Feb 24, 2003
Grant date	Mar 9, 2004
Priority date	—
Expiry date	Feb 24, 2023

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D401/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to novel 1,2,3,4-tetrahydroisochinoline derivatives of formula (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.