Platelet-derived growth factor D

US6706687B1 · kind B1 · utility

Assignees

• LUDWIG INSTITUTE FOR CANCER RESEARCH LTD · GB
• Helsinki University · FI

Inventors

• Ulf Eriksson
• Karin Aase · Stockholm, SE
• Xuri Lee · Stockholm, SE
• Annica Ponten · Stockholm, SE
• Marko Uutela · Helsinki, FI
• Kari Alitalo · Helsinki, FI
• Arne Oestman · Uppsala, SE
• Carl-Henrik Heldin · Uppsala, SE

Key dates

• Filing date: Nov 10, 1999
• Grant date: Mar 16, 2004
• Expiry date: Nov 10, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

PDGF-D, a new member of the PDGF/VEGF family of growth factors, is described, as well as the nucleotide sequence encoding it, methods for producing it, antibodies and other antagonists to it, transfected and transformed host cells expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.