Patent · US Expired

Alpha-amino-acid compounds

US6706742B2 · kind B2 · utility

62Cited by
1References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 15, 2002
Grant dateMar 16, 2004
Priority date
Expiry dateJun 2, 2022

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compound selected from those of formula (I): wherein: represents an optionally substituted 5-membered nitrogen-containing heterocycle,Ak represents an alkylene chain,X represents a single bond or phenylene,R1 and R2, which may be identical or different, each represent hydrogen or alkyl,R3 represents alkyl, nitro or cyano,Y represents NR4 or CHNO2,R4 represents hydrogen or alkyl,its tautomers when they exist, its optical isomers, and addition salts thereof with a pharmaceutically acceptable acid,with the exclusion of compounds wherein, simultaneously, represents an unsubstituted 5-membered nitrogen-containing heterocycle, Ak represents —(CH2)3—, X represents a single bond, Y represents NH and R3 represents nitro.Medicinal products containing the same which are useful as dipeptidyl peptidase IV inhibitors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.