Bioactivated diagnostic imaging contrast agents
US6709646B2 · kind B2 · utility
2Cited by
9References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 14, 2001 |
| Grant date | Mar 23, 2004 |
| Priority date | — |
| Expiry date | Dec 22, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/106
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to improved diagnostic agents for Magnetic Resonance Imaging and optical imaging. In particular, this invention relates to MRI and optical imaging agents that allow for the sensitive detection of a specific bloactivity within a tissue. These agents are prodrug contrast agents which are bioactivated in vivo in the presence of the specific bioactivity. This invention also relates to pharmaceutical compositions comprising these agents and to methods of using the agents and compositions comprising the agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.