Easy to swallow oral medicament composition
US6709678B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Feb 10, 1999 |
| Grant date | Mar 23, 2004 |
| Priority date | — |
| Expiry date | Feb 10, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5073
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance, the particles being combined with one or more gelling or swelling agents capable of forming a viscous medium around the particles in an aqueous carrier as well as being provided with a masking surface layer when dispersed in the aqueous carrier. This serves to mask uneven surfaces on the particles and prevent them from adhering to oral mucosa when the composition is ingested and thus makes it easier to administer large dosages of an active substance. The masking surface layer is preferably provided by an increased viscosity of the viscous medium in the immediate vicinity of the particles relative to the viscosity of the surrounding aqueous carrier. A ready-to-use composition is prepared by mixing the composition with an aqueous carrier substantially immediately prior to administration of the composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.