Target-dependent reactions using structure-bridging oligonucleotides
US6709815B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 18, 2000 |
| Grant date | Mar 23, 2004 |
| Priority date | — |
| Expiry date | Jul 18, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A90/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to methods and compns. for treating nucleic acids, and in particular, methods and compns. for the detection and characterization of nucleic acid sequences and sequence changes. The invention provides methods for examg. the conformations assumed by single strands of nucleic acid, forming the basis of novel methods of detection of specific nucleic acid sequences. The present invention contemplates use of novel detection methods for, among other uses, clinical diagnostic purposes, including but not limited to the detection and identification of pathogenic organisms. Examples are presented for the analysis of Mycobacterium tuberculosis and hepatitis C virus genes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.