Process for the synthesis of a known tetrazol derivative
US6710183B2 · kind B2 · utility
2Cited by
1References
8Claims
0Family size
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Key dates
| Filing date | Jul 24, 2002 |
| Grant date | Mar 23, 2004 |
| Priority date | — |
| Expiry date | Jul 24, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A Process is disclosed for preparing a compound of the Formula (I) which comprises the steps of:(a) detritylating a compound of the Formula (III)  with 0.1 to 1 equivalent of potassium hydroxide in a C1 to C4 straight chain alcohol solvent to obtain a reaction mixture containing the compound of the Formula (I),(b) changing the C1 to C4 straight chain alcohol solvent in the reaction mixture to an aprotic solvent or a weakly protic solvent, and(c) following step (b) crystallizing out the compound of the Formula (I) from the reaction mixture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.