Process and device for separation with variable-length chromatographic zones
US6712973B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 26, 2002 |
| Grant date | Mar 30, 2004 |
| Priority date | — |
| Expiry date | Mar 26, 2022 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/1821
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A process for separating at least one component of a mixture in a set of closed-loop chromatographic columns is described, whereby the loop comprises at least one feedstock injection point, a raffinate draw-off point, an eluant injection point, and an extract draw-off point, in which a determination is made between an injection point and a draw-off point or vice-versa a chromatographic zone, and at the end of a given period of time, all of the injection points and draw-off points are shifted by the same number of columns or column sections and advantageously by one column or column section in a given direction that is defined relative to that of the flow of a main fluid that circulates through the loop. During the period, the shifting of different injection points and draw-off points of at least one column or column section is done at different times in such a way that the lengths of the zones that are defined by said different points are variable. The process is useful for the separation particularly of stereoisomers for pharmaceuticals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.