Detecting genetic predisposition to sight-threatening diabetic retinopathy
US6713253B1 · kind B1 · utility
7Cited by
4References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 10, 1998 |
| Grant date | Mar 30, 2004 |
| Priority date | — |
| Expiry date | Mar 10, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method and kit for predicting increased risk of sight-threatening diabetic retinopathy which includes isolating genomic DNA from a sample from a diabetic patient. The genetic polymorphism pattern for the genes IL-1A, IL-1B and IL-1RN is then identified in the DNA. The identified pattern is compared with control patterns of known polymorphisms, and patients expressing a genetic polymorphism pattern associated with increased risk of sight-threatening diabetic retinopathy are identified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.