Tea polyphenol esters and analogs thereof for cancer prevention and treatment
US6713506B2 · kind B2 · utility
10Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 11, 2001 |
| Grant date | Mar 30, 2004 |
| Priority date | — |
| Expiry date | Oct 11, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are ester-bond containing tea polyphenols that has a susceptibility to nucleophilic attack, their analogs and pharmaceutically acceptable salts, method for inhibiting proteasomal chymotrypsin-like activity in vivo and in vitro, methods for cancer treatment with tea-derived polyphenols, such as EGCG, ECG, GCG, or CG, as well as pharmaceutical compositions comprising the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.