Method for production of microcapsules
US6716456B1 · kind B1 · utility
2Cited by
6References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 25, 2001 |
| Grant date | Apr 6, 2004 |
| Priority date | — |
| Expiry date | Oct 25, 2021 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J13/10
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention provides a process for microencapsulating a pharmaceutical substrate comprising the steps of: a) adding insoluble or sparingly soluble particles of the substrate to be microencapsulated to a stable buffer solution having a high ionic strength; b) dissolving a membrane-forming ionic polymer in the buffer; c) forming a coacervate by adding a water-complexing compound causing phase separation of the resulting mixture; and d) allowing the deposition of the coacervate onto the substrate so as to create a coating of polymer around the substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.