Nucleic acids encoding a chloride channel protein
US6716603B2 · kind B2 · utility
1Cited by
2References
18Claims
0Family size
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Key dates
| Filing date | Oct 16, 2002 |
| Grant date | Apr 6, 2004 |
| Priority date | — |
| Expiry date | Oct 16, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/927
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered. The invention also includes a method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.