Metalloprotease having aggrecanase activity
US6716613B1 · kind B1 · utility
1Cited by
1References
10Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 10, 2001 |
| Grant date | Apr 6, 2004 |
| Priority date | — |
| Expiry date | Jan 23, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides a novel metalloprotease having an aggrecanase activity which causes joint diseases, a gene coding for this metalloprotease, a promoter of the above metalloprotease, a method for screening a drug with the use of the above metalloprotease and a pharmaceutical composition for inhibiting degradation of proteoglycans, which comprises as the active ingredient a substance capable of inhibiting the aggrecanase activity of the above metalloprotease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.