Compounds having affinity for the granulocyte-colony stimulating factor receptor (G-CSFR) and associated uses
US6716811B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 20, 2000 |
| Grant date | Apr 6, 2004 |
| Priority date | — |
| Expiry date | Sep 1, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel compounds are provided that bind to G-CSFR. The novel compounds have a peptide chain approximately 6 to 40 amino acids in length that binds to G-CSFR. The compounds are useful as probes for affinity screening. In addition, the compounds have demonstrated agonist or antagonist activity for the G-CSFR, and are therefore useful in treatment of diseases including patients who suffer from a low white blood cell titer. Pharmaceutical compositions and methods of use are provided as well.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.