Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US6716870B2 · kind B2 · utility
3Cited by
24References
23Claims
0Family size
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Inventors
Key dates
| Filing date | Sep 16, 2002 |
| Grant date | Apr 6, 2004 |
| Priority date | — |
| Expiry date | Sep 16, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65583
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to prodrugs of certain 3-(pyrrol-2-yl-methylidene)-2-indolinone derivatives that modulate the activity of protein kinases (“PKs”). Pharmaceutical compositions comprising these compounds, methods of treating diseases related to abnormal PK activity utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.