Substituted pyrrolidine-2,3,4-trione 3-oxime derivatives which are active as NMDA receptor antagonists

US6716872B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Michael Przewosny · Aachen, DE
• Hans-Dietrich Stachel · Schwanau, DE
• Hermann Poschen-Rieder · Gräfelfing, DE

Key dates

• Filing date: Feb 6, 2002
• Grant date: Apr 6, 2004
• Expiry date: Feb 6, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel substituted pyrrolidine-2,3,4-trione compounds of formula I and methods for preparing the compounds. Also disclosed are pharmarceutical compositions comprising the compounds and methods of using the compounds for treating pain, anxiety and various other diseases or conditions.